阿洛司他丁,>95.0%(HPLC)
E-64d [for Biochemical Research]
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中文名称:
阿洛司他丁
英文名称:
E-64d [for Biochemical Research]
CAS No.:
88321-09-9
分子式:
C₁₇H₃₀N₂O₅
分子量:
342.43
熔点:
126.2°C
沸点:
477.88°C (rough estimate)
闪点:
279.2°C
溶解性:
DMSO:6.9 mg/mL (20 mM)
保存条件:
-20℃
InChIKey:
SRVFFFJZQVENJC-IHRRRGAJSA-N
InChI:
InChI=1S/C17H30N2O5/c1-6-23-17(22)14-13(24-14)16(21)19-12(9-11(4)5)15(20)18-8-7-10(2)3/h10-14H,6-9H2,1-5H3,(H,18,20)(H,19,21)/t12-,13-,14-/m0/s1
Pubchem ID:
危化品级别:
危害声明:
H315-H319-H335
警示性声明:
P261-P305+P351+P338
危险类别码:
R36/37/38
关于的化合物详细属性等信息,点击“阿洛司他丁”
阿洛司他丁用途是什么?
提问时间:2021/7/23 13:04:35
阿洛司他丁是做什么用的?哪里可以用到阿洛司他丁?
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回复内容:
1
admin2021-07-23 13:04:35
阿洛司他丁一种cysteine protease(半胱氨酸蛋白酶)抑制剂。The compound can permeate an intact cell and block the activity of calpain, which results in the protection of protein kinase C (PKC) from proteolysis. E-64-d is also a cathepsin B, cathepsin H, and cathepsin L inhibitor. Research shows that E-64-d can enhance compromised natural killer cells and bactericidal activity of leukocytes. In addition, E-64-d has been shown to induce cell cycle arrest during prophase and metaphase in Xenopus embryonic cells.
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