Recombin human MARK3 protein,BR

基因名: MARK3
别名: C-TAK1;Cdc25C associated protein kinase 1;Cdc25C-associated protein kinase 1;cTAK1;ELKL motif kinase 2;EMK-2;Emk2;ETK 1;KIAA4230;KP78;MAP microtubule affinity regulating kinase 3;MAP/microtubule affinity-regulating kinase 3;Mark3;MARK3_HUMAN;Par 1a;PAR1A;Protein kinase STK10;Ser/Thr protein kinase PAR-1;Serine threonine protein kinase p78;Serine/threonine-protein kinase p78;SerThr protein kinase PAR 1;
英文名称: Recombinant human MARK3 protein
全名: MAP/microtubule affinity-regulating kinase 3
中文名称: 微管亲和调控蛋白激酶3
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件: The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

Swiss Prot： P27448
Gene ID： 4140
交叉反应： Human Mouse Rat
分子量： 39kDa
区间范围： 42-392aa
背景说明： Serine/threonine-protein kinase (PubMed:23666762).Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4.Phosphorylates the microtubule-associated protein MAPT/TAU (PubMed:23666762).Phosphorylates CDC25C on 'Ser-216'.Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus (PubMed:16980613).Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1.Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1 (PubMed:28087714).
应用： Immunology research
来源： E.coli

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

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