Recombin human RAB40B protein,BR

基因名:RAB40B
英文全称:RAB40B, member RAS oncogene family
别称:CREBBP;CBP;KAT3A;RSTS;RSTS1
中文名称:RAB40B,RAS致癌基因家族成员
Uniprot:Q12829
GeneID:10966
交叉反应(推测):Human Mouse
氨基酸大小:31kDa
表达氨基酸:1-279aa
Background:This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors.First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition.The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex.This protein acetylates both histone and non-histone proteins.This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain.Mutations in this gene cause Rubinstein-Taybi syndrome (RTS).Chromosomal translocations involving this gene have been associated with acute myeloid leukemia.Alternative splicing results in multiple transcript variants encoding different isoforms.
Application:Immunology research
Derived from:E.coli
Purification:NI-NTA affinity purification
Formulation:Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0.
Shipping:The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
Storage:Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°c="" for="" 2-3="">
Reconstitution:Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Purity:Purity≥85% as determined by reducing SDS-PAGE.
Endotoxin:/
规格:10ug, 50ug, 100ug, 1mg, 注意：
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