Recombinant human CNOT8 protein,BR

基因名： CNOT8
别名： CAF1;CALIF;Caf1b;POP2;hCAF1
全名： CCR4-NOT transcription complex，subunit 8
英文名称： Recombinant Human CNOT8 Protein
中文名称： CCR4-NOT转录复合物，亚基8
规格： 50ug ; 100ug ; 1mg ; 10ug
外观(性状)： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度： ≥85% by SDS-PAGE.
储存条件： Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件： 冷藏运输
浓度： 1mg/ml by SDS-PAGE.

Swiss Prot： Q9UFF9
Gene ID： 9337
交叉反应： Human Mouse
分子量： 34kDa
区间范围： 1-292aa
背景说明： Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate.Its function seems to be partially redundant with that of CNOT7.Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation.Additional complex functions may be a consequence of its influence on mRNA expression.Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.
应用： Immunology research
来源： E.coli

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： NO
标签信息： With a 6×His tag at the N/C-terminus.

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