Recombinant human CCDC134 protein,BR

基因名： CCDC134
别名： FLJ22349
全名： coiled-coil domain containing 134
英文名称： Recombinant Human CCDC134 Protein
中文名称： 含Coiled-coil 结构域蛋白134
规格： 10ug ; 50ug ; 100ug ; 1mg
外观(性状)： Liquid: Supplied as a 0.2 μm filtered solution of 20mM Tris, 0.5M NaCl, 10% Gly, pH8.0.
纯度： ≥85% by SDS-PAGE.
储存条件： Reconstituted protein solution can be stored at < -70°C for 6 months.Please minimize freeze-thaw cycles.
运输条件： 干冰运输
浓度： 1mg/ml by SDS-PAGE.

Swiss Prot： Q9H6E4
Gene ID： 79879
交叉反应： Human Mouse Rat
分子量： 27kDa
区间范围： 1-229aa
背景说明： In extracellular secreted form, promotes proliferation and activation of CD8+ T cells, suggesting a cytokine-like function (PubMed:25125657).Enhances cytotoxic anti-tumor activity of CD8+ T cells (PubMed:25125657).May inhibit ERK and JNK signaling activity (PubMed:18087676, PubMed:23070808).May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling (PubMed:23070808).In the nucleus, enhances stability of the PCAF histone acetyltransferase (HAT) complex member TADA2A and thus promotes PCAF-mediated H3K14 and H4K8 HAT activity.May inhibit TADA2A-mediated TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity.May also promote TADA2A-mediated XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage.
应用： Immunology research
来源： E.coli

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： NO
标签信息： With a 6×His tag at the N/C-terminus.

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