Recombinant human ALDH4A1 protein,BR

基因名： ALDH4A1
别名： TRIP10;CIP4;HSTP;STOT;STP;TRIP-10;cdc42-interacting protein 4
全名： aldehyde dehydrogenase 4 family，member A1
英文名称： Recombinant Human ALDH4A1 Protein
中文名称： δ-1-吡咯啉-5-羧酸脱氢酶
规格： 10ug ; 50ug ; 100ug ; 1mg
外观(性状)： Liquid: Supplied as a 0.2 μm filtered solution of 20mM Tris, 0.5M NaCl, 10% Gly, pH8.0.
纯度： ≥85% by SDS-PAGE.
储存条件： Reconstituted protein solution can be stored at < -70°C for 6 months.Please minimize freeze-thaw cycles.
运输条件： 干冰运输
浓度： 1mg/ml by SDS-PAGE.

Swiss Prot： P30038
Gene ID： 8659
交叉反应： Human (Bovine Mouse Rat Zebrafish)
分子量： 38kDa
区间范围： 214-563aa
背景说明： Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling.Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis.Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules.Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex.Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles.Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells.May be required for the lysosomal retention of FASLG/FASL.
研究领域： 代谢性疾病研究
应用： Immunology research
来源： E.coli

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： NO
标签信息： With a 6×His tag at the N/C-terminus.

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