Recombin human COPS2 protein,BR

基因名: COPS2
别名: COPS2;ALIEN;CSN2;SGN2;TRIP15;COP9 signalosome subunit 2
全名: COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)
英文名称: Recombinant human COPS2 protein
中文名称: COP9信号小体复合体亚基2
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件: The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

Swiss Prot： P61201
Gene ID： 9318
交叉反应： Human Mouse Rat (Zebrafish)
分子量： 50kDa
区间范围： 1-440aa
背景说明： Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2.The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases.CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.Involved in early stage of neuronal differentiation via its interaction with NIF3L1.
应用： Immunology research
来源： E.coli

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

暂无数据

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