Recombin human RHBDD1 protein,BR

基因名: RHBDD1
别名: RHBDD1;RRP4;rhomboid-related protein 4
全名: rhomboid domain containing 1
英文名称: Recombinant human RHBDD1 protein
中文名称: rhomboid相关蛋白4
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件: The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

Swiss Prot： Q8TEB9
Gene ID： 84236
交叉反应： Human Mouse Rat (Gorilla)
分子量： 12kDa
区间范围： 1-106aa
背景说明： Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions.Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded membrane proteins.Required for the degradation process of some specific misfolded endoplasmic reticulum (ER) luminal proteins.Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner.Functions in BIK, MPZ, PKD1, PTCRA, RHO, STEAP3 and TRAC processing.Involved in the regulation of exosomal secretion; inhibits the TSAP6-mediated secretion pathway.Involved in the regulation of apoptosis; modulates BIK-mediated apoptotic activity.Also plays a role in the regulation of spermatogenesis; inhibits apoptotic activity in spermatogonia.
应用： Immunology research
来源： E.coli

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

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