Recombinant human PNRC2 protein,BR

基因名： PNRC2
别名： HSPC208
全名： proline-rich nuclear receptor coactivator 2
英文名称： Recombinant Human PNRC2 Protein
中文名称： 富含脯氨酸核受体辅活化子2
规格： 10ug ; 50ug ; 100ug ; 1mg
外观(性状)： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度： ≥85% by SDS-PAGE.
储存条件： Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件： 冷藏运输
浓度： 1mg/ml by SDS-PAGE.

Swiss Prot： Q9NPJ4
Gene ID： 55629
交叉反应： Human Mouse Rat (Bovine)
分子量： 16kDa
区间范围： 1-139aa
背景说明： Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery .May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs (PubMed:19150429).Required for UPF1/RENT1 localization to the P-body .Plays a role in glucocorticoid receptor-mediated mRNA degradation by interacting with the glucocorticoid receptor NR3C1 in a ligand-dependent manner when it is bound to the 5' UTR of target mRNAs and recruiting the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay.Also acts as a nuclear receptor coactivator (PubMed:11574675).May play a role in controlling the energy balance between energy storage and energy expenditure.
应用： Immunology research
来源： E.coli

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： NO
标签信息： With a 6×His tag at the N/C-terminus.

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