Recombinant Human BTN2A2,BR

别名： Butyrophilin subfamily 2 member A2;BTN2A2
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

背景说明： Butyrophilin 2A2 (BTN2A2) is a widely expressed type I transmembrane glycoprotein that functions as a negative regulator of immune responses.Mature human Butyrophilin 2A2 consisits of a 233 amino acid (aa) extracellular domain with two immunoglobulin-like domains，a 21 aa transmembrane segment，and a 237 aa cytoplasmic domain.Alternative splicing generates additional isoforms of human Butyrophilin 2A2 that lack the first，second，or both Iglike domains as well as isoforms with substitutions and deletions in the cytoplasmic region.Within the immune system，Butyrophilin 2A2 is expressed on thymic epithelial cells，native B cells，splenic NK cells，dendritic cells，and peritoneal macrophages and is up-regulated with cell activation.Butyrophilin 2A2 inhibits T cell proliferation and activation and enhances the development of FoxP3+ regulatory T cells.Its up-regulation in the hippocampus is associated with schizophrenia.
来源： Human Cells

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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