Recombinant Human Tryptophan 5-hydroxylase 2/TPH-2,BR

别名： Tryptophan 5-Hydroxylase 2;Neuronal Tryptophan Hydroxylase;Tryptophan 5-Monooxygenase 2;TPH2;NTPH
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
纯度: ≥80% as determined by reducing SDS-PAGE.
储存条件: Store at≤-70℃，6 months.with seal;3 month after opening.Avoid freeze/thaw cycles.

背景说明： Tryptophan 5-hydroxylase 2 (TPH2) is an isozyme member of the biopterin-dependent aromatic amino acid hydroxylase family.TPH2 is primarily expressed in the serotonergic neurons of the brain，with the highest expression found in the raphe nucleus of the midbrain.TPH2 catalyzes the first and rate limiting step in the biosynthesis of serotonin，an important hormone and neurotransmitter.Genetic variation in TPH2 may influence susceptibility to major depressive disorder (MDD).Defects in TPH2 are the cause of psychiatric diseases such as bipolar affective disorder and major depression.
来源： E.coli

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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