Recombinant Human CD177/PRV1,BR

别名： CD177 Antigen;Human Neutrophil Alloantigen 2a;HNA-2a;NB1 Glycoprotein;NB1 GP;Polycythemia Rubra Vera Protein 1;PRV-1;CD177;NB1;PRV1
英文名称： Recombinant Human CD177/PRV1
中文名称： 重组人CD177/PRV1
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
纯度： ≥95% as determined by reducing SDS-PAGE.
储存条件： Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： 冷藏运输

背景说明： CD177 is polymorphic and has at least two alleles: PRV1 and NB1.Human PRV1 is a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein that belongs to the uPAR/CD59/Ly6 family of receptors.PRV1 is expressed by neutrophils and neutrophil precursors，and changes in expression serve as diagnostic markers for myeloproliferative disorders such as polycythemia vera and essential thrombocythemia.PRV1 may also be expressed by Erythroblasts，B cells，and Monocytes.NB1，a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein，was first described in a case of neonatal alloimmune neutropenia.It is reported that CD177 functions as a novel heterophilic binding partner that engages PECAM-1 in membrane-proximal IgD6.
来源： Human Cells

溶剂： Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素： Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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