Recombinant Human Calnexin/IP90/CANX,BR

别名： Calnexin;IP90;Major Histocompatibility Complex Class I Antigen-Binding Protein p88;p90;CANX
英文名称： Recombinant Human Calnexin/IP90/CANX
中文名称： 重组人Calnexin/IP90/CANX
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 2mM CaCl2, 10% Glycerol, pH 7.5.
纯度： ≥95% as determined by reducing SDS-PAGE.
储存条件： Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
运输条件： 干冰运输

背景说明： Calnexin/CANX is a single-pass type I membrane protein which belongs to the calreticulin family.It consists of a large N-terminal calcium-binding lumenal domain，a single transmembrane helix and a short (90 residues)，acidic cytoplasmic tail.The function of calnexin is to retain unfolded or unassembled N-linked glycoproteins in the endoplasmic reticulum.Calnexin is a calcium-binding protein that interacts briefly with newly synthesized glycoproteins in the endoplasmic reticulum.Calnexin may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits.Calnexin seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.Calnexin dwindles with aging and might contribute to a cytoprotection in an array of human age-related diseases.
来源： Human Cells

内毒素： Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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