Recombinant Human APE/APE1/APEX,BR

别名： DNA-(Apurinic or Apyrimidinic Site) Lyase;APEX Nuclease;APEN;Apurinic-Apyrimidinic Endonuclease 1;AP Endonuclease 1;APE-1REF-1;Redox Factor-1;APEX1;APE;APE1;APEX;APX;HAP1;REF1
英文名称： Recombinant Human APE/APE1/APEX
中文名称： 重组人APE/APE1/APEX
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 10mM HEPES, 100mM KCl, 50% Glycerol, pH 7.4.
纯度： ≥95% as determined by reducing SDS-PAGE.
储存条件： Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
运输条件： 干冰运输

背景说明： Apurinic-Apyrimidinic Endonuclease 1 (APE1) is required for efficient DNA base excision repair.When the DNA glycosylase remove the damaged bases，APE1 cleaves the AP site to allow resynthesis and ligation to complete repair.APE1 stimulates the DNA binding activity of many transcription factors，which participate in cancer promotion and progression.APE1 regulates the redox state of multiple transcription factors，such as c-Jun，c-Fos，NF-kB，p53.APEN is also involved in calcium-dependent down-regulation of PTH expression.
来源： E.coli

内毒素： Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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