Recombinant Human Pre-B-Cell Colony-Enhancing Factor 1/PBEF/Visfatin/NAMPT/Nicotinamide phosphoribosyltransferase,BR

别名： Pre-B cell-enhancing factor;Nicotinamide phosphoribosyltransferase;NAmPRTase;Nampt;Pre-B-cell colony-enhancing factor 1;Visfatin;NAMPT;PBEF;PBEF1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, pH8.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

背景说明： Pre-B cell colony enhancing factor (PBEF) was originally identified as a cytokine that potentiated the clonal expansion and differentiation of pre-B cells，but it is also acknowledged to be the ubiquitous intracellular enzyme nicotinamide phosphoribosyltranferase (NAMPT) and the adipokine “visfatin”.PBEF is constitutively expressed in the fetal membranes where its greatest expression is in the amnion.It has intracellular and extracellular forms.Most of the intracellular functions of PBEF are due to its role as a Nampt which can induce angiogenesis through upregulation of VEGF and VEGFR and secretion of MCP-1.Extracellular PBEF has been shown to increase inflammatory cytokines，such as TNF-α，IL-1β，IL-16，and TGF-β1.PBEF also increases the production of IL-6，TNF-α，and IL-1β in CD14+ monocyctes，macrophages，and dendritic cells，enhances the effectiveness of T cells.
来源： E.coli

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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