Recombinant Mouse LMIR1/CD300A,BR

别名： CD300a;CD300a antigen;CMRF35H9;CD300a molecule;leukocyte immunoglobulin-like receptor;CD300 antigen-like family member A;CMRF35-like molecule 8;NK inhibitory receptor;Immunoglobulin superfamily member 12;IRp60;Inhibitory receptor protein 60;CLM8;CMRF-35H;IGSF12;IRC1;IRC2;LMIR1;CLM-8;MAIR-I
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

背景说明： LMIR1，also termed CD300a，is a type I transmembrane glycoprotein with a single IgV-like extracellular domain and an extended membrane proximal region that links the immunoglobulin (Ig) and transmembrane domains and belongs to the immunoglobulin superfamily.The intracellular domain of LMIR1 contains several immunoreceptor tyrosine-based inhibition motifs (ITIMs).When cross-linked，it will be tyrosine phosphorylated and capable of recruiting tyrosine phosphatases (SHP-1，SHP-2) and inositol polyphosphate 5-phosphatase，SHIP.LMIR1 will regulate mast cell-mediated inflammatory responses.LMIR1 is broadly expressed on myeloid and lymphoid cells，and its expression is differentially regulated depending on the cell type.
来源： Human Cells

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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