Recombinant Human Thrombomodulin,BR

别名： Thrombomodulin;THBD;TM;Fetomodulin;CD141;THRM
英文名称： Recombinant Human Thrombomodulin
中文名称： Recombinant Human Thrombomodulin
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH8.0.
纯度： ≥95% as determined by reducing SDS-PAGE.
储存条件： Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
运输条件： 干冰运输

背景说明： Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin.This complex is responsible for the conversion of protein C to the activated protein C (protein Ca).Human Thrombomodulin/THBD predicts a signal peptide and a mature chain that consists of following domains: C-type lectin，EGF-like，transmembrane and cytoplasmic.Predominantly synthesized by vascular endothelial cells，THBD inhibits coagulation and fibrinolysis.THBD gene polymorphisims are associated with human disease and THBD plays a role in thrombosis，stroke，arteriosclerosis，and cancer.For example，increased serum levels of THBD，due to protease cleavage，have been associated with smoking，cardiac surgery，atherosclerosis，liver cirrhosis，diabetes mellitus，cerebral and myocardial infarction，and multiple sclerosis.
来源： Human Cells

内毒素： Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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