Recombinant Human CD112/Nectin-2/Pvrl2/Pvr/Mph/Pvs,BR

别名： Poliovirus Receptor-Related Protein 2;Herpes Virus Entry Mediator B;Herpesvirus Entry Mediator B;HveB;Nectin-2;CD112;PVRL2;HVEB;PRR2
英文名称： Recombinant Human CD112/Nectin-2/Pvrl2/Pvr/Mph/Pvs
中文名称： Recombinant Human CD112/Nectin-2/Pvrl2/Pvr/Mph/Pvs
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
纯度： ≥95% as determined by reducing SDS-PAGE.
储存条件： Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： 冷藏运输

背景说明： CD112 is a type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily.It comprises one Ig-like V-type domain and two Ig-like C2-type domains in the extracellular region.The V domain is believed to mediate nectin binding to its ligands.Nectin2 is known to bind the pseudorabies virus，and herpes simplex virus2 (HSV2)，involving in cell to cell spreading of these viruses.It does not bind poliovirus.As a homophilic adhesion molecule，CD112 is found concentrated in adherens junctions，and exists on neurons，endothelial cells，epithelial cells and fibroblasts.CD112 has been identified as the ligand for DNAM-1 (CD226)，and the interaction of CD226/CD112 mediates cytotoxicity and cytokine secretion by T and NK cells.The costimulatory responses may be a critical component in allergic reactions and may therefore become targets for anti-allergic therapy.
来源： Human Cells

溶剂： Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素： Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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