Recombinant Mouse Ectodysplasin A2 Receptor/EDA2R/TNFRSF27,BR

别名： Ectodysplasin A2 receptor;EDA-A2 receptor;EDA-A2R;Tumor necrosis factor receptor superfamily member XEDAR;Tumor necrosis factor receptor superfamily member 27;X-linked ectodysplasin-A2 receptor;EDAA2R;TNFRSF27;XEDAR;EDAR2
英文名称： Recombinant Mouse Ectodysplasin A2 Receptor/EDA2R/TNFRSF27
中文名称： Recombinant Mouse Ectodysplasin A2 Receptor/EDA2R/TNFRSF27
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度： ≥95% as determined by reducing SDS-PAGE.
储存条件： Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： 冷藏运输

背景说明： Tumor necrosis factor receptor superfamily member 27，also known as XEDAR and EDA2R，is a type III transmembrane protein of the TNFR superfamily.EDA2R consists of extracellular domain (ECD) with 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide.EDA2R is widely expressed，notably in embryonic basal epidermal cells and maturing hair follicles.Even though it does not contain a cytoplasmic death domain，EDA2R can associate with Fas and induce EDA-A2 dependent apoptosis.Its transcription is directly induced by p53，and it mediated cell death is p53 dependent.it is down-regulated in breast，colon，and lung cancers，particularly in cases with p53 mutations.It also plays a role in EDA-A2 induced skeletal muscle degeneration and osteoblast differentiation.Mutations in the EDA gene are associated with the X-linked form of Hypohidrotic Ectodermal Dysplasia (HED)，a disease typically characterized by abnormal hair，teeth and sweat glands.
来源： Human Cells

溶剂： Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素： Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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