Recombinant Cynomolgus Nectin-4/PVRL4,BR

别名： PVRL4;Nectin-4;Ig superfamily receptor LNIR;Poliovirus receptor-related protein 4;PRR4;LNIR
中文名称: Recombinant Cynomolgus Nectin-4/PVRL4
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

背景说明： Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins.It contains two Ig-like C2-type domains and one Ig-like V-type domain.PVRL4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions，the latter including specifically interactions with nectin-1.It does not act as receptor for alpha-herpesvirus entry into cells.It is predominantly expressed in placenta，the embryo and breast carcinoma.But it is not detected in normal breast epithelium.The soluble form is produced by proteolytic cleavage at the cell surface (shedding)，probably by ADAM17.Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1，an autosomal recessive disorder.
来源： Human Cells

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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