Recombinant Human CD99/MIC2/MIC2X/MIC2Y,BR

别名： CD99 Antigen;12E7;E2 Antigen;Protein MIC2;T-Cell Surface Glycoprotein E2;CD99;MIC2;MIC2X;MIC2Y
英文名称： Recombinant Human CD99/MIC2/MIC2X/MIC2Y
中文名称： 重组人CD99/MIC2/MIC2X/MIC2Y
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
纯度： ≥95% as determined by reducing SDS-PAGE.
储存条件： Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： 冷藏运输

背景说明： CD99 is a type I transmembrane glycoprotein and the founding member of the CD99 family of molecules.The extracellular domain of CD99 contains no identifiable motifs，its cytoplasmic region，although short，does have signal transduction capability.Cells known to express CD99 include fibroblasts，neutrophils，T cells，double positive thymocytes，CD34+ stem cells，monocytes and endothelial cells.Two types of CD99 isoforms have been classified.Native human CD99 is referred to as the long，or type I isoform.The best studied type II isoform shows an Asp-Gly substitution for the C terminal 27 amino acids.The type I and II isoforms have distinctive signal transduction pathways (FAKsrc for type I PI3K plus srcERK1/2 for type II)，and mediate clearly different biological outcomes.Homophilic interaction between CD99 on the neutrophil and CD99 on the endothelial cell regulates the transendothelial migration of neutrophils during inflammation.Human CD99 has 48% aa sequence identity to mouse CD99.
来源： Human Cells

溶剂： Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素： Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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