Recombinant Human ALK-2/Activin RIA,BR

别名： Activin Receptor Type-1;Activin Receptor Type I;ACTR-I;Activin Receptor-Like Kinase 2;ALK-2;Serine/Threonine-Protein Kinase Receptor R1;SKR1;TGF-B Superfamily Receptor Type I;TSR-I;ACVR1;ACVRLK2
中文名称: Recombinant Human ALK-2/Activin RIA
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

背景说明： Activin receptor type-1，also known as Activin receptor type I，Activin receptor-like kinase 2，Serine/threonine-protein kinase receptor R1，TGF-B superfamily receptor type I，ACVRLK2 and ACVR1，is a single-pass type I membrane protein.ACVR1 is expressed in normal parenchymal cells，endothelial cells，fibroblasts and tumor-derived epithelial cells.ACVR1 belongs to the protein kinase superfamily.Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors.These receptors are all transmembrane proteins，composed of a ligand-binding extracellular domain with cysteine-rich region，a transmembrane domain，and a cytoplasmic domain with predicted serine/threonine specificity.Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors.Type I and II receptors form a stable complex after ligand binding，resulting in phosphorylation of type I receptors by type II receptors.ACVR1 signals a particular transcriptional response in concert with activin type II receptors.
来源： Human Cells

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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