Recombinant Human BMPR-II/PPH1/BMPR2/BMP type II receptor,BR

别名： Bone Morphogenetic Protein Receptor Type-2;BMP Type-2 Receptor;BMPR-2;Bone Morphogenetic Protein Receptor Type II;BMP Type II Receptor;BMPR-II;BMPR2;PPH1
中文名称: Recombinant Human BMPR-II/PPH1/BMPR2/BMP type II receptor
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

背景说明： Bone Morphogenetic Protein Receptor II (BMPR-II) is a Type II Serine/Threonine Kinase that mediates cellular responses to BMPs.BMPR-II is characterized by lacking of a GS domain，and presence of a C-terminal extension typical of type II receptors.BMPRII binds BMP2，BMP4 and BMP7 weakly in the absence of type I receptor，and the binding can be facilitated by the presence of the type I receptor，including BMPR-IA/Brk1，BMPR-IB，and ActR-I.BMPR-II plays a key role in cell growth.Defects in BMPR-II have been linked to primary pulmonary hypertension.Human and mouse BMPR-II are highly conserved and share 97 % amino acid sequence identity.
来源： Human Cells

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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