Recombinant Human ALCAM/CD166,BR

别名： CD166 antigen;Activated leukocyte cell adhesion molecule;CD166;ALCAM;MEMD
英文名称： Recombinant Human ALCAM/CD166
中文名称： Recombinant Human ALCAM/CD166
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度： ≥95% as determined by reducing SDS-PAGE.
储存条件： Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： 冷藏运输

背景说明： Activated leukocyte cell adhesion molecule (ALCAM)，also named as CD166 and MEMD，is a typeI transmembrane glycoprotein of immunoglobulin superfamily，which mediates homotypic and heterotypic interactions between cells.ALCAM is expressed on thymic epithelium，microvascular endothelium，activated lymphocytes and monocytes，and monocytederived dendritic cells.ALCAM mediates low-affinity adhesion with itself or the cysteine-rich scavenger receptor CD6 to regulate T cell development，immunological synapses(IS)，and cell migration through endothelial junctions.ALCAM on thymic epithelia mediates adhesion to CD6 on CD4+CD8+ T cells.Adhesion of ALCAM expressing antigen presenting cells and CD6-expressing T cells stabilizes the early IS，while later it enhances CD3 effects on T cell proliferation，CD25 expression，and Th1 commitment.ALCAM may influence expression or adhesion of the neuronal adhesion molecule NCAML1，both in the developing retina and invasive melanoma.
来源： Human Cells

溶剂： Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素： Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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