Anti-TCF7L2 Polyclonal Antibody,BR

英文名称： Anti-TCF7L2 Polyclonal Antibody
中文名称： 转录因子7类似物2抗体
规格： 50ul ; 100ul ; 20ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应： Human ; Mouse
应用： IHC-P
稀释比例： IHC-P 1:100-300.

靶标： TCF7L2
别名： E2 2, HMG box transcription factor 4, hTCF 4, Immunoglobulin transcription factor 2, ITF2, SEF2 1, SEF2 1A, SEF2 1B, SEF2, T cell factor 4, T cell specific HMG box, T cell specific transcription factor 4, TCF 4, TCF4, TCF7L2, TCF7L2 protein, hTCF-4, T-cell factor 4, T-cell-specific transcription factor 4, TCF-4, TF7L2_HUMAN, Transcription factor 7-like 2, Transcription factor 4, Transcription factor 7 like 2, Transcription factor 7 like 2 T cell specific HMG box
背景说明： Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1. Necessary for the maintenance of the epithelial stem-cell compartment of the small intestine.
Swiss Prot： Q9NQB0
Gene ID： 6934
亚细胞定位： Nucleus
免疫原： A synthetic peptide of human TCF7L2Public Immunogen Range 435-485/619aa
理论分子量： 55/68kDa

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。