Anti-RPSA Polyclonal Antibody,BR

英文名称： Anti-RPSA Polyclonal Antibody
中文名称： 核糖体蛋白SA抗体
规格： 50ul ; 100ul ; 20ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应： Mouse ; Rat ; Human预测
交叉反应： Cow(92.9%);Rabbit(100%);Chicken(100%);Pig(92.9%);Monkey(100%);Sheep(85.7%);Hamster(100%);Zebrafish(100%);Fish(100%);Bird(100%)
应用： WB ; IHC-P
稀释比例： WB 1:5000-8000. IHC-P 1:50-200.

靶标： RPSA
别名： 37/67 kDa laminin receptor;37LRP;40S ribosomal protein SA;67 kDa laminin receptor;67LR;LAMBR;Laminin receptor;Laminin receptor 1;LamR;LAMR1;LBP/p40;LRP;LRP/LR;NEM/1CHD4;p40;ribosomal protein SA;RPSA
背景说明： Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
Swiss Prot： P08865
Gene ID： 3921
亚细胞定位： Cytoplasm Nucleus Cell membrane
研究领域： 细胞生物学 ; 干细胞
免疫原： A synthetic peptide of human RPSA 种属同源性预测Public Immunogen Range 245-295/295aa
理论分子量： 33kDa

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.
运输条件： 冷冻运输 种属同源性预测

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。