Anti-CD163 Polyclonal Antibody,BR

英文名称： Anti-CD163 Polyclonal Antibody
中文名称： CD163抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应： Rat ; Mouse ; Human预测
交叉反应： Rat;Dog;Pig;Horse
应用： WB ; IHC-P ; IHC-F ; IF
稀释比例： WB 1:500-2000. IHC-P 1:100-500. IHC-F 1:100-500. IF 1:100-500.

靶标： CD163
别名： Scavenger receptor cysteine-rich type 1 protein M130;CD 163;CD163 antigen;CD163 molecule;Hemoglobin Scavenger Receptor;M130;M130 antigen precursor;Macrophage associated antigen;MM130
背景说明： Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells.
Swiss Prot： Q86VB7
Gene ID： 9332
亚细胞定位： Cell membrane Secreted
研究领域： 免疫学 ; 细胞生物学
免疫原： A synthetic peptide of human CD163Public Immunogen Range 1001-1121/1156aa
理论分子量： 125/121kDa

纯化方法： Affinity purification
储存液： 0.01M TBS (pH7.4) with 1% BSA， 0.02% Proclin300 and 50% Glycerol.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.
运输条件： 冷冻运输

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。