Anti-HIF 2 alpha Polyclonal Antibody,BR

英文名称： Anti-HIF 2 alpha Polyclonal Antibody
中文名称： 缺氧诱导因子2α /HIF-2α/HIF-2-alpha抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human预测
交叉反应：： Pig;Cow;Horse
应用： ELISA ; FCM ; IF ; IHC ; WB
稀释比例： WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. FCM 1μg/Test. IF 1:100-500.

靶标： HIF 2 alpha
别名： EPAS 1;EPAS-1;EPAS1;EPAS1_HUMAN;HIF 1 alpha like factor;HIF 2 alpha;HIF-1-alpha-like factor;HIF-2-alpha;HIF2-alpha;HIF2A
背景说明： Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBPB and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD.
Swiss Prot： P97481
Gene ID： 13819
亚细胞定位： Cytoplasm Nucleus
免疫原： A synthetic peptide of mouse HIF 2 alpha
Public Immunogen Range： 1-130/874aa
理论分子量： 96kDa

纯化方法： Affinity purification
储存液： 0.01M TBS(pH7.4) with 1% BSA，0.03% Proclin300 and 50% Glycerol.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

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