Anti-MSH6 Polyclonal Antibody,BR

英文名称： Anti-MSH6 Polyclonal Antibody
中文名称： 错配修复蛋白6抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应： Human ; Mouse
应用： WB ; IF-C
稀释比例： WB 1:500-1000. IF-C 1:50-100.

靶标： MSH6
别名： GTBP;GTMBP;HNPCC5;HSAP;p160
背景说明： This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.
Swiss Prot： P52701
Gene ID： 2956
亚细胞定位： Chromosome Nucleus
研究领域： 表观遗传
免疫原： Recombinant protein of human MSH6Public Immunogen Range 1061-1360aa
理论分子量： 153kDa

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.
运输条件： 冷冻运输

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

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