Anti-AIFM1 Polyclonal Antibody,BR

英文名称： Anti-AIFM1 Polyclonal Antibody
中文名称： 凋亡诱导因子，线粒体相关蛋白1抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应： Mouse ; Rat ; Human
应用： WB ; IHC-P ; IF/ICC ; ELISA
稀释比例： WB 1:500-1000. IHC-P 1:50-200. IF/ICC 1:50-200.

靶标： AIFM1
别名： AIF;CMT2D;CMTX4;COWCK;COXPD6;DFNX5;NADMR;NAMSD;PDCD8
背景说明： This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and mental retardation. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.
Swiss Prot： O95831
Gene ID： 9131
亚细胞定位： Cytoplasm Mitochondrion inner membrane Mitochondrion intermembrane space Nucleus perinuclear region
研究领域： 细胞生物学
免疫原： Recombinant protein of human AIFM1Public Immunogen Range 334-613aa
理论分子量： 67kDa

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.
运输条件： 冷冻运输

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

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