Anti-IL10 Polyclonal Antibody,BR

英文名称:Anti-IL10 Polyclonal Antibody
宿主:Rabbit
别名:IL10;CSIF;GVHDS;IL-10;IL10A;TGIF;interleukin-10

交叉反应:Human Mouse Rat
应用:WB IHC
稀释比例:WB 1:500-1:2000. IHC 1:50-1:100.
蛋白分子量:20kDa
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG
免疫原:Recombinant protein of human IL10
亚细胞定位:Secreted
Swiss Prot:P22301
背景资料:The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.
克隆类型:Polyclonal Antibody
规格:50ul, 100ul, 注意：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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