Anti-CACNA2D2 Polyclonal Antibody,BR

英文名称： Anti-CACNA2D2 Polyclonal Antibody
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse
应用： WB
稀释比例： WB 1:200-2000

靶标： CACNA2D2
别名： CACNA2D2,KIAA0558,Voltage-dependent calcium channel subunit alpha-2/delta-2,Voltage-gated calcium channel subunit alpha-2/delta-2,[Cleaved into: Voltage-dependent calcium channel subunit alpha-2-2, Voltage-dependent calcium channel subunit delta-2]
背景说明： Calcium channels mediate the entry of calcium ions into the cell upon membrane polarization. This gene encodes the alpha-2/delta subunit of the voltage-dependent calcium channel complex. The complex consists of the main channel-forming subunit alpha-1, and auxiliary subunits alpha-2/delta, beta, and gamma. The auxiliary subunits function in the assembly and membrane localization of the complex, and modulate calcium currents and channel activation/inactivation kinetics. The subunit encoded by this gene undergoes post-translational cleavage to yield the extracellular alpha2 peptide and a membrane-anchored delta polypeptide. This subunit is a receptor for the antiepileptic drug, gabapentin. Mutations in this gene are associated with early infantile epileptic encephalopathy. Single nucleotide polymorphisms in this gene are correlated with increased sensitivity to opioid drugs. Alternative splicing results in multiple transcript variants encoding different isoforms.
Swiss Prot： Q9NY47
Gene ID： 9254
亚细胞定位： Membrane Single-pass type I membrane protein
免疫原： Recombinant protein of human CACNA2D2
Public Immunogen Range： 20-200aa
理论分子量： 130/122kDa

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。