人CD86分子检测yabo官网手机版 盒,BR

中文名称： 人CD86分子检测yabo官网手机版 盒
英文名称： Human CD86 ELISA Kit
别名： Cluster Of Differentiation 86; CD86; B7-2; Activation B7-2 Antigen; B70; B7-2 Antigen; B72; BU63; CD28 Antigen Ligand 2; CD86 Antigen; CD86 Molecule; FUN-1; LAB72
储存条件： 2-8℃，6 months
规格： 48T ; 96T
检测目标： CD86
样品类型： 血清/血浆/细胞培养上清
反应性： Human
应用： ELISA
定量/定性： 定量检测
检测范围： 46.875-3000pg/mL
灵敏度： 23.4375pg/mL
精密度： 板内，板间变异系数均<10%
回收率： 80%-120%

Swiss Prot： P42081
Gene ID： 942
背景说明： CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B and T helper cells mediated by CD86 encourage signals for the proliferation and IgG secretion of normal B cells and B cell lymphomas. Recent study has revealed that CD86 also promotes the generation of a mature APC repertoire and promotes APC function and survival. CD86 has an important role in chronic hemodialysis, allergic pulmonary inflammation, arthritis, and antiviral responses, and thus is regarded as a promising candidate for immune therapy.

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