人成纤维细胞生长因子受体2检测yabo官网手机版 盒,BR
Human FGFR2/CD332 ELISA KIT
(订货以英文名为准)
产品编号：AC16527
品牌：Acmec
人成纤维细胞生长因子受体2检测yabo官网手机版 盒
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中文名称：
人成纤维细胞生长因子受体2检测yabo官网手机版
盒
英文名称：
Human FGFR2/CD332 ELISA KIT
保存条件：
2-8℃
中文名称： 人成纤维细胞生长因子受体2检测yabo官网手机版
盒
英文名称： Human FGFR2 ELISA Kit
别名： Fibroblast Growth Factor Receptor 2; BBDS; BEK; BFR-1; CD332; CEK3; CFD1; craniofacial dysostosis 1; ECT1; FGFR2; Jackson-Weiss syndrome; JWS; Keratinocyte growth factor receptor like 14; KGFR; KSAM; soluble FGFR4 variant 4; TK14
储存条件： 2-8℃，6 months
规格： 48T ; 96T
检测目标： FGFR2/CD332
样品类型： 血清/血浆/细胞培养上清
反应性： Human
应用： ELISA
定量/定性： 定量检测
检测范围： 43.75-2800pg/mL
灵敏度： 22pg/mL
精密度： 板内，板间变异系数均<10%
回收率： 80%-120% Swiss Prot： P21802
Gene ID： 2263
背景说明： FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. It is required for normal embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis and skin development. FGFR2 plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. It also promotes cell proliferation in keratinocytes and imature osteoblasts, but promotes apoptosis in differentiated osteoblasts. FGFR2 signaling is down-regulated by ubiquitination, internalization and degradation. Mutations that lead to constitutive kinase activation or impair normal CD332 maturation, internalization and degradation lead to aberrant signaling. Over-expressed FGFR2 promotes activation of STAT1. Defects in CD3322 are the cause of Crouzon syndrome, Jackson-Weiss syndrome, Apert syndrome, Pfeiffer syndrome, Beare-Stevenson cutis gyrata syndrome, familial scaphocephaly syndrome, lacrimo-auriculo-dento-digital syndrome and Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis. 暂无数据 1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。
英文名称： Human FGFR2 ELISA Kit
别名： Fibroblast Growth Factor Receptor 2; BBDS; BEK; BFR-1; CD332; CEK3; CFD1; craniofacial dysostosis 1; ECT1; FGFR2; Jackson-Weiss syndrome; JWS; Keratinocyte growth factor receptor like 14; KGFR; KSAM; soluble FGFR4 variant 4; TK14
储存条件： 2-8℃，6 months
规格： 48T ; 96T
检测目标： FGFR2/CD332
样品类型： 血清/血浆/细胞培养上清
反应性： Human
应用： ELISA
定量/定性： 定量检测
检测范围： 43.75-2800pg/mL
灵敏度： 22pg/mL
精密度： 板内，板间变异系数均<10%
回收率： 80%-120% Swiss Prot： P21802
Gene ID： 2263
背景说明： FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. It is required for normal embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis and skin development. FGFR2 plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. It also promotes cell proliferation in keratinocytes and imature osteoblasts, but promotes apoptosis in differentiated osteoblasts. FGFR2 signaling is down-regulated by ubiquitination, internalization and degradation. Mutations that lead to constitutive kinase activation or impair normal CD332 maturation, internalization and degradation lead to aberrant signaling. Over-expressed FGFR2 promotes activation of STAT1. Defects in CD3322 are the cause of Crouzon syndrome, Jackson-Weiss syndrome, Apert syndrome, Pfeiffer syndrome, Beare-Stevenson cutis gyrata syndrome, familial scaphocephaly syndrome, lacrimo-auriculo-dento-digital syndrome and Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis. 暂无数据 1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。
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