犬瘦素Elisayabo官网手机版 盒,BR

中文名称： 犬瘦素检测yabo官网手机版 盒
英文名称： Canine Leptin ELISA Kit
别名： FLJ94114; LEP; leptin (murine obesity homolog); leptin (obesity homolog, mouse); Leptin; OB; Obese protein; obese, mouse, homolog of; Obesity factor; OBOBS
储存条件： 2-8℃，6 months
规格： 48T ; 96T
检测目标： Leptin
样品类型： 血清/血浆/细胞培养上清
反应性： Canine
应用： ELISA
定量/定性： 定量检测
检测范围： 25-1600pg/mL
灵敏度： 5pg/mL
精密度： 板内，板间变异系数均<10%
回收率： 80%-120%

Swiss Prot： O02720
Gene ID： 403616
背景说明： Adipose cells produce and secrete numerous physiologically important proteins, such as lipoprotein lipase (LPL), leptin and adiponectin protein of 30 kDa. Adiponectin is a circulating protein that is secreted exclusively by differentiated adipocytes. During adipocyte differentiation, mRNA levels of Adiponectin have been shown to be induced over 100-fold. Studies indicate that Adiponectin enhances the ability of sub-physiological levels of insulin to suppress glucose production, thus linking adipose tissue to whole body glucose regulation. Adiponectin function appears to be regulated by phosphatidylinositol-3-kinase (PI3-K) since Adiponectin secretion is blocked by pharmacologic inhibitors of this kinase. mRNA levels of Adiponectin have been shown to be significantly reduced in adipose tissue of obese patients with Type 2 diabetes relative to control subjects. Structural similarities to TNFalpha suggests that Adiponectin may play a role in pathogenesis of insulin resistance in Type 2 diabetes. Because Adiponectin is down-regulated in various forms of obesity and its structural similarity to TNFalpha, it is currently being investigated as an important regulator of whole body energy homeostasis.

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