Recombinant Human ACE-2 (C-6His),BR

别名： Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase; Angiotensin-Converting Enzyme Homolog; ACEH; Metalloprotease MPROT15; ACE2
英文名称: ACE-2(Mammalian，C-6His)
中文名称: ACE-2(Mammalian，C-6His)
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状): Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl， 300mM NaCl， 1mM ZnCl2， 10% Glycerol， pH 7.4.
纯度： Greater than 95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C， stable for 6 months after receipt. Store at ≤-70°C， stable for 3 months under sterile conditions after opening.Please minimize freeze thaw cycles.
运输条件: 干冰运输

Swiss Prot： Q9BYF1
分子量： 84.63 KDa
表观分子量： 103 KDa， reducing conditions
区间范围： Gln18-Ser740
背景说明: Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family， the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase， ACE-2 converts angiotensin I to angiotensin 1-9， and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis， kidney and heart， in colon， small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
来源： Human Cells

内毒素： < 1 EU/μg as determined by LAL test.
标签信息： C-6His

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