Recombinant 2019-nCoV S1 Protein (C-Fc),BR

英文名称: S1 Protein (Mammalian，C-Fc)
中文名称: S1蛋白 (Mammalian，C-Fc)
规格: 50ug ; 500ug ; 1mg
外观(性状): Supplied as a 0.2 μm filtered solution of PBS， pH 7.4
纯度： Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
储存条件: Store at ≤-70°C， stable for 6 months after receipt. Store at ≤-70°C， stable for 3 months under sterile conditions after opening.Please minimize freeze thaw cycles.
运输条件: 干冰运输

Swiss Prot： QHD43416.1
分子量： 102.2kDa
背景说明: The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It’s been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits， S1 and S2. S1 mainly contains a receptor binding domain (RBD)， which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses， as well as protective immunity.

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