Recombinant Mouse Interleukin-23 Receptor/IL-23R,BR

别名： Interleukin-23 receptor;Il23r;IL-23 receptor;IL-23R;interleukin 23 receptor
英文名称： Recombinant Mouse Interleukin-23 Receptor/IL-23R
中文名称： 重组小鼠Interleukin-23 Receptor/IL-23R
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度： ≥95% as determined by reducing SDS-PAGE.
储存条件： Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： 冷藏运输

背景说明： Interleukin 23 receptor (IL23R)，a heterodimer of the IL12 receptor β1 (IL12Rβ1) and IL12Rβ2，is a type I cytokine receptor for IL23.IL23R is comprised of two subunits，the IL12Rβ1 subunit，which is shared with several cytokines，and a subunit that is unique to IL-23.IL23，after binding to IL23R，activates memory T cells and mediates pro-inflammatory activities in part by the production of IL17 through activation of TH17 lymphocytes.IL23R is expressed on T cells，NK cells，dendritic cells，and macrophages.In fact，polymorphisms of the IL23R gene were reported to be associated with susceptibility to inflammatory diseases and autoimmune diseases such as psoriasis，multiple sclerosis，Graves's ophtalmopathy and inflammatory bowel diseases.The IL23R is known to be critically involved in the carcinogenesis of different malignant tumor.
来源： Human Cells

溶剂： Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素： Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.

Recombinant Mouse Interleukin-23 Receptor is produced by our Mammalian expression system and the target gene encoding Gly24-Asp372 is expressed with a Fc tag at the C-terminus.

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