Recombinant Mouse IL-4,BR

别名： Interleukin-4;B-cell IgG differentiation factor;B-cell growth factor 1;B-cell stimulatory factor 1;IGG1 induction factor;Lymphocyte stimulatory factor 1;IL-4;BSF-1
英文名称： Recombinant Mouse IL-4
中文名称： 重组小鼠IL-4
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 5% Sucrose, 4% Mannitol, 0.1% PS-80, pH 6.5.
纯度： ≥95% as determined by reducing SDS-PAGE.
储存条件： Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： 冷藏运输

背景说明： Mouse Interleukin-4(IL-4) is a monomeric，Th2 cytokine that shows pleiotropic effects during immune responses.It is a glycosylated polypeptide that contains three intrachain disulfide bridges and adopts a bundled four α-helix structure.IL-4 exerts its effects through two receptor complexes，Participates in at least several B-cell activation processes as well as of other cell types.IL-4 is primarily expressed by Th2-based CD4+T cells，mast cells，basophils，and eosinophils.It promotes cell proliferation，survival，and immunoglobulin class switch to IgG1 and IgE in mouse B cells，acquisition of the Th2 phenotype by native CD4+T cells，priming and chemotaxis of mast cells，eosinophils，and basophils，and the proliferation and activation of epithelial cells.IL-4 plays a dominant role in the development of allergic inflammation and asthma.It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
来源： E.coli

溶剂： Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素： Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

Recombinant Mouse Interleukin-4 is produced by our E.coli expression system and the target gene encoding His23-Ser140 is expressed.

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