Recombinant Human IL-23(IL23A&IL12B),BR

别名： SGRF;IL-23p19;CLMF p40;IL-12 subunit p40;NKSF2
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： The product is shipped at ambient temperature.

背景说明： Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits，a p19 subunit that is unique to IL-23，and a p40 subunit that is shared with IL-12.The p19 subunit has homology to the p35 subunit of IL-12，as well as to other single chain cytokines such as IL-6 and IL-11.The p40 subunit is homologous to the extracellular domains of the hematopoietic cytokine receptors.Although p19 is expressed by activated macrophages，dendritic cells，T cells，and endothelial cells，only activated macrophages and dendritic cells express p40 concurrently to produce IL-23.IL-23 has biological activities that are similar to，but distinct from IL-12.Both IL-12 and IL-23 induce proliferation and IFN-gamma production by human T cells.While IL-12 acts on both naive and memory human T cells，the effects of IL-23 is restricted to memory T cells.
来源： Human cells

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.

Recombinant Human Interleukin-23  is produced by our Mammalian expression system and the target gene encoding Arg20-Pro189&Ile23-Ser328 is expressed with a 6His tag at the C-terminus.

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