Recombinant Human Cadherin-3/CDH3,BR

别名： Cadherin-3;Placental Cadherin;P-Cadherin;CDH3;CDHP
英文名称： Recombinant Human Cadherin-3/CDH3
中文名称： 重组人Cadherin-3/CDH3
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度： ≥95% as determined by reducing SDS-PAGE.
储存条件： Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： 冷藏运输

背景说明： Cadherin-3 (CDH3) is a single-pass type I membrane protein that belongs to the cadherin superfamily.CDH3 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats，a transmembrane region，and a highly conserved cytoplasmic tail.CDH3 is expressed in some normal epithelial tissues and in some carcinoma cell lines.CDH3 preferentially interacts with themselves in a homophilic manner in connecting cells.CDH3 is involved in loss of heterozygosity events in breast and prostate cancer.Mutations in CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.
来源： Human Cells

溶剂： Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素： Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.

Recombinant Human Cadherin-3 is produced by our Mammalian expression system and the target gene encoding Glu25-Gly654 is expressed with a 6His tag at the C-terminus.

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