Recombinant Human B7-2/CD86,BR

别名： T-Lymphocyte Activation Antigen CD86;Activation B7-2 Antigen;B70;BU63;CTLA-4 Counter-Receptor B7.2;FUN-1;CD86;CD28LG2
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： The product is shipped at ambient temperature.

背景说明： The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production，by binding CD28 or CTLA-4.It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells，such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation.Isoform 2 interferes with the formation of CD86 clusters，and thus acts as a negative regulator of T-cell activation.The protein interacts with MARCH8，human herpesvirus 8 MIR2 protein，adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.It contains 1 Ig-like C2-type(immunoglobulin-like) domainand 1 Ig-like V-type (immunoglobulin-like) domain.
来源： Human cells

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.

Recombinant Human CD86 is produced by our Mammalian expression system and the target gene encoding Ala24-Pro247 is expressed with a 6His tag at the C-terminus.

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