Recombinant Human IL-18,BR

别名： Interleukin-18;Iboctadekin;Interferon gamma-inducing factor;IFN-gamma-inducing factor;Interleukin-1 gamma;IL-1 gamma;GIF;IL-18;IL-1g;IL1F4;MGC12320
英文名称： Recombinant Human IL-18
中文名称： 重组人IL-18
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度： ≥95% as determined by reducing SDS-PAGE.Less than 0.1 ng/g (1 IEU/g).
储存条件： Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： 冷藏运输

区间范围： YFGKLESKLSVIRNLNDQVLFIDQGNRPLFEDMTDSDCRDNAPRTIFIISMYKDSQPRGMAVTISVKCEKISTLSCENKIISFKEMN PPDNIKDTKSDIIFFQRSVPGHDNKMQFESSSYEGYFLACEKERDLFKLILKKEDELGDRSIMFTVQNED
背景说明： Interleukin-18 is a secreted protein and it belongs to the IL-1 family.IL-18 is a proinflammatory cytokine and produced by macrophages and other cells.This cytokine can induce the IFN-gamma production of T cells.The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production，and enhance IgG2a production of B cells.IL-18 binding protein (IL18BP) can specifically interact with this cytokine，and thus negatively regulate its biological activity.After stimulation with IL-18，natural killer (NK) cells and certain T cells release another important cytokine called interferon-γ (IFN-γ) or type II interferon that plays an important role in activating the macrophages or other cells.
来源： E.coli

溶剂： Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in 8X PBS.Please aliquot the reconstituted solution to minimize freeze-t cycles.

Recombinant Human Interleukin-18 is produced by our E.coli expression system and the target gene encodingTyr37-Asp193 is expressed.

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