别名：SC-514;C9H8N2OS2
CAS：354812-17-2 分子式：C₉H₈N₂OS₂ 分子量：224.30 MDL：MFCD00206459

S41380	CAS:354812-17-2	4-氨基-[2,3'-二噻吩]-5-甲酰胺, 98%, Acmec		价格库存收藏产品

化合物信息
安全信息

中文名称：

SC-514

英文名称：

SC514

CAS No.：

354812-17-2

分子式：

C₉H₈N₂OS₂

分子量：

224.30

InChIKey：

BMUACLADCKCNKZ-UHFFFAOYSA-N

InChI：

InChI=1S/C9H8N2OS2/c10-6-3-7(5-1-2-13-4-5)14-8(6)9(11)12/h1-4H,10H2,(H2,11,12)

Pubchem ID：

2807869

GHS符号：

信号词：

危险

危害声明：

H301

警示性声明：

P301 + P310

技术问答

游客JZ2108199430 2021-08-19 09:09

问 SC-514用途是什么？

描述：SC-514是做什么用的?哪里可以用到SC-514?

答 SC-514A cell-permeable (thienothienyl)amino-acetamide compound that displays anti-inflammatory properties. Acts as a potent, reversible, ATP-competitive, and highly selective inhibitor of IKK-2 (IC50 ~3-12 碌M for IKK-2 homodimer, IKK-1/IKK-2 heterodimer, and IKK-2). Its specificity has been confirmed using a panel of 31 other kinases, including IKK isoforms IKK-1, IKK-i, and TBK-1 (IC50 > 200 碌M). Shown to specifically block NF-kB-dependent gene expression, but not MAP kinase pathways, in stimulated synovial fibroblasts RASF.

admin 2021-08-19 09:09

SC-514A cell-permeable (thienothienyl)amino-acetamide compound that displays anti-inflammatory properties. Acts as a potent, reversible, ATP-competitive, and highly selective inhibitor of IKK-2 (IC50 ~3-12 碌M for IKK-2 homodimer, IKK-1/IKK-2 heterodimer, and IKK-2). Its specificity has been confirmed using a panel of 31 other kinases, including IKK isoforms IKK-1, IKK-i, and TBK-1 (IC50 > 200 碌M). Shown to specifically block NF-kB-dependent gene expression, but not MAP kinase pathways, in stimulated synovial fibroblasts RASF.

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技术问答

问 SC-514用途是什么？