别名：2-氰基-3-羟基-N-(4-三氟甲基苯基)巴豆酰胺;特立氟胺;C12H9F3N2O2
CAS：108605-62-5 分子式：C₁₂H₉F₃N₂O₂ 分子量：270.21 MDL：MFCD00910058

C11840	CAS:108605-62-5	2-氰基-3-羟基-N-(4-(三氟甲基)苯基)丁-2-烯酰胺, 99%, Acmec		价格库存收藏产品

化合物信息
安全信息

中文名称：

2-氰基-3-羟基-N-(4-三氟甲基苯基)巴豆酰胺

英文名称：

Teriflunomide(Random Configuration)

CAS No.：

108605-62-5

分子式：

C₁₂H₉F₃N₂O₂

分子量：

270.21

InChIKey：

UTNUDOFZCWSZMS-YFHOEESVSA-N

InChI：

InChI=1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7-

Pubchem ID：

54684141

GHS符号：

信号词：

Warning

危害声明：

H302

警示性声明：

P280-P305+P351+P338

技术问答

游客JZ2106309300 2021-06-30 13:00

问特立氟胺用途是什么？

描述：特立氟胺是做什么用的?哪里可以用到特立氟胺?

答特立氟胺用途Teriflunomide, aslo known as A77 1726, is the active metabolite of leflunomide. Teriflunomide is an immunomodulatory drug inhibiting pyrimidine de novo synthesis by blocking the enzyme dihydroorotate dehydrogenase. It is uncertain whether this explains its effect on MS lesions. Teriflunomide inhibits rapidly dividing cells, including activated T cells, which are thought to drive the disease process in MS. It has been found that teriflunomide blocks the transcription factor NF-κB. The drug was approved by the FDA on September 13, 2012.

admin 2021-08-19 09:09

特立氟胺用途Teriflunomide, aslo known as A77 1726, is the active metabolite of leflunomide. Teriflunomide is an immunomodulatory drug inhibiting pyrimidine de novo synthesis by blocking the enzyme dihydroorotate dehydrogenase. It is uncertain whether this explains its effect on MS lesions. Teriflunomide inhibits rapidly dividing cells, including activated T cells, which are thought to drive the disease process in MS. It has been found that teriflunomide blocks the transcription factor NF-κB. The drug was approved by the FDA on September 13, 2012.

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技术问答

问 特立氟胺用途是什么？

问特立氟胺用途是什么？